There is no abstract available for this article.

Interest statement

Compliance and ethics The author(s) declare that they have no conflict of interest.


[1] Bao L., Jin S.X., Zhang C., Wang L.H., Xu Z.Z., Zhang F.X., Wang L.C., Ning F.S., Cai H.J., Guan J.S., Xiao H.S., Xu Z.Q.D., He C., Hökfelt T., Zhou Z., Zhang X.. Activation of Delta Opioid Receptors Induces Receptor Insertion and Neuropeptide Secretion. Neuron, 2003, 37: 121-133 CrossRef Google Scholar

[2] Bao L., Wang H.F., Cai H.J., Tong Y.G., Jin S.X., Lu Y.J., Grant G., Hökfelt T., Zhang X.. Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord. Eur J Neuroscience, 2002, 16: 175-185 CrossRef Google Scholar

[3] Guan J.S., Xu Z.Z., Gao H., He S.Q., Ma G.Q., Sun T., Wang L.H., Zhang Z.N., Lena I., Kitchen I., Elde R., Zimmer A., He C., Pei G., Bao L., Zhang X.. Interaction with Vesicle Luminal Protachykinin Regulates Surface Expression of δ-Opioid Receptors and Opioid Analgesia. Cell, 2005, 122: 619-631 CrossRef PubMed Google Scholar

[4] He S.Q., Zhang Z.N., Guan J.S., Liu H.R., Zhao B., Wang H.B., Li Q., Yang H., Luo J., Li Z.Y., Wang Q., Lu Y.J., Bao L., Zhang X.. Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation. Neuron, 2011, 69: 120-131 CrossRef PubMed Google Scholar

[5] Li C.L., Li K.C., Wu D., Chen Y., Luo H., Zhao J.R., Wang S.S., Sun M.M., Lu Y.J., Zhong Y.Q., Hu X.Y., Hou R., Zhou B.B., Bao L., Xiao H.S., Zhang X.. Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity. Cell Res, 2016, 26: 83-102 CrossRef PubMed Google Scholar

[6] Li K.C., Zhang F.X., Li C.L., Wang F., Yu M.Y., Zhong Y.Q., Zhang K.H., Lu Y.J., Wang Q., Ma X.L., Yao J.R., Wang J.Y., Lin L.B., Han M., Zhang Y.Q., Kuner R., Xiao H.S., Bao L., Gao X., Zhang X.. Follistatin-like 1 Suppresses Sensory Afferent Transmission by Activating Na+,K+-ATPase. Neuron, 2011, 69: 974-987 CrossRef PubMed Google Scholar

[7] Liu X.J., Zhang F.X., Liu H., Li K.C., Lu Y.J., Wu Q.F., Li J.Y., Wang B., Wang Q., Lin L.B., Zhong Y.Q., Xiao H.S., Bao L., Zhang X.. Activin C expressed in nociceptive afferent neurons is required for suppressing inflammatory pain. Brain, 2012, 135: 391-403 CrossRef PubMed Google Scholar

[8] Wang F., Cai B., Li K.C., Hu X.Y., Lu Y.J., Wang Q., Bao L., Zhang X.. FXYD2, a γ subunit of Na+,K+-ATPase, maintains persistent mechanical allodynia induced by inflammation. Cell Res, 2015, 25: 318-334 CrossRef PubMed Google Scholar

[9] Wang H.B., Zhao B., Zhong Y.Q., Li K.C., Li Z.Y., Wang Q., Lu Y.J., Zhang Z.N., He S.Q., Zheng H.C., Wu S.X., Hökfelt T.G.M., Bao L., Zhang X.. Coexpression of  - and  -opioid receptors in nociceptive sensory neurons. Proc Natl Acad Sci USA, 2010, 107: 13117-13122 CrossRef PubMed ADS Google Scholar

[10] Wu Q.F., Yang L., Li S., Wang Q., Yuan X.B., Gao X., Bao L., Zhang X.. Fibroblast Growth Factor 13 Is a Microtubule-Stabilizing Protein Regulating Neuronal Polarization and Migration. Cell, 2012, 149: 1549-1564 CrossRef PubMed Google Scholar

[11] Xiao H.S., Huang Q.H., Zhang F.X., Bao L., Lu Y.J., Guo C., Yang L., Huang W.J., Fu G., Xu S.H., Cheng X.P., Yan Q., Zhu Z.D., Zhang X., Chen Z., Han Z.G., Zhang X.. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc Natl Acad Sci USA, 2002, 99: 8360-8365 CrossRef PubMed ADS Google Scholar

[12] Yang L., Dong F., Yang Q., Yang P.F., Wu R., Wu Q.F., Wu D., Li C.L., Zhong Y.Q., Lu Y.J., Cheng X., Xu F.Q., Chen L., Bao L., Zhang X.. FGF13 Selectively Regulates Heat Nociception by Interacting with Na v 1.7. Neuron, 2017, 93: 806-821.e9 CrossRef PubMed Google Scholar

[13] Zhang F.X., Liu X.J., Gong L.Q., Yao J.R., Li K.C., Li Z.Y., Lin L.B., Lu Y.J., Xiao H.S., Bao L., Zhang X.H., Zhang X.. Inhibition of Inflammatory Pain by Activating B-Type Natriuretic Peptide Signal Pathway in Nociceptive Sensory Neurons. J Neuroscience, 2010, 30: 10927-10938 CrossRef Google Scholar

[14] Zhang X., Bao L., Guan J.S.. Role of delivery and trafficking of δ-opioid peptide receptors in opioid analgesia and tolerance. Trends Pharmacological Sci, 2006, 27: 324-329 CrossRef PubMed Google Scholar

[15] Zhang X., Bao L., Li S.. Opioid receptor trafficking and interaction in nociceptors. Br J Pharmacol, 2015, 172: 364-374 CrossRef PubMed Google Scholar

[16] Zhao B., Wang H.B., Lu Y.J., Hu J.W., Bao L., Zhang X.. Transport of receptors, receptor signaling complexes and ion channels via neuropeptide-secretory vesicles. Cell Res, 2011, 21: 741-753 CrossRef PubMed Google Scholar

Copyright 2020 Science China Press Co., Ltd. 《中国科学》杂志社有限责任公司 版权所有

京ICP备17057255号       京公网安备11010102003388号