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SCIENCE CHINA Life Sciences, Volume 61, Issue 11: 1304-1309(2018) https://doi.org/10.1007/s11427-018-9353-5

Clinical application of magnetically controlled capsule gastroscopy in gastric disease diagnosis: recent advances

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  • ReceivedJul 20, 2018
  • AcceptedAug 23, 2018
  • PublishedOct 18, 2018

Abstract

Magnetically controlled capsule gastroscopy (MCCG) is a novel system primarily used for the diagnosis of gastric disease. It consists of an endoscopic capsule with magnetic material inside, external guidance magnet equipment, data recorder and computer workstation. Several clinical trials have demonstrated that MCCG is comparable in accuracy in diagnosing gastric focal disease when compared to conventional gastroscopy. Further clinical studies are needed to test the diagnostic accuracy and improve the functioning of MCCG. This novel MCCG system could be a promising alternative for screening for gastric diseases, with the advantages of no anesthesia required, comfort and high acceptance across populations.


Funded by

the Chang Jiang Scholars Program of Ministry of Education(Q2015190toZhaoshenLi)

China and the Shanghai Health and Family Planning Commission Plans to Excellent Leaders(2017BR005toZhuanLiao)


Acknowledgment

This work was supported by the Chang Jiang Scholars Program of Ministry of Education, China (Q2015190 to Zhuan Liao) and the Shanghai Health and Family Planning Commission Plans to Excellent Leaders (2017BR005 to Zhuan Liao).


Interest statement

The author(s) declare that they have no conflict of interest.


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  • Figure 1

    (Color online) Robotic MCCG system from China Ankon (Copyright owned by Dr. Zhuan Liao (Liao et al., 2016)).

  • Table 1   Table 1Comparison of three MCCG systems

    Features

    Capsule endoscopes

    Olympus & Siemens

    Given imaging

    Ankon NaviCam

    General information

    Size (mm)

    31×11

    31×11

    28×12

    Weight (g)

    NA

    7

    5.2

    Battery life (h)

    NA

    10

    8–10

    Resolution

    NA

    256×256

    480×480

    Frames per second

    4

    4

    2

    Field of view

    145°

    156°

    140°

    Depth of field (mm)

    0–30

    0--30

    0–30

    FDA approval

    No

    No

    Yes (CFDA, 2013)

    Control system

    Control method

    MRI guidance (multiple coils carrying current, electromagnetic field)

    Permanent magnet with manual paddle control

    Permanent magnet with robotic control

    Maximum magnetic field @ working area

    100 mT

    NA

    200 mT

    Control distance (air)

    NA

    13 cm

    20 cm

    Control distance (water)

    >25 cm

    15 cm

    25 cm

    Maximum continuous magnetic force at 25 cm distance

    1 mN

    4.0 mN

    21.7 mN

    MCE control feedback signals

    Images plus calculated capsule orientation

    Images only

    Images plus calculated and measured capsule location

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