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Chinese Science Bulletin, Volume 64, Issue 10: 1001-1007(2019) https://doi.org/10.1360/N972018-00888

Chiral plasmonic nanostructures via DNA self-assembly

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  • ReceivedAug 29, 2018
  • AcceptedOct 30, 2018
  • PublishedDec 12, 2018

Abstract

Controlling molecular chirality is of great importance in nanotechnology. Many biologically active molecules are chiral, including the naturally occurring amino acids, nuclear acids and sugars. In biological systems, most of these compounds are of the same chirality and the circular dichroism (CD) response of natural molecules is very weak. On the other hand, when metallic nanostructures, especially noble metal, illuminated by light with proper energy and momentum, surface plasmons can be excited, which have been used to enhance the electric field and excite higher electric and magnetic modes, leading to a series of fantastic optical phenomena and applications. Chirality of natural molecules can be manipulated by reconfiguring molecular structures through light, electric field, and thermal stimuli. While, the fabrication of complex metal structures is limited by the condition of current technology, especially for the precise fabrication and manipulation molecules at the nanoscale. Moreover, how to achieve chiroptical response in the visible range needs more efforts. In recent years, DNA nanotechnology, using DNA as building blocks of self-assembly, could be finely engineered into desired nanoarchitectures with high complexity and precision. It provides an effective way to easily control and tailor the arrangement of nanoparticles, and to form chiral metamolecules with complicated geometry. Among a variety of functionalized particles, metal nanoparticles such as gold nanoparticles feature an important pathway to endow DNA origami assembled nanostructures with tailored optical functionalities. Such DNA nanostructures were used for building versatile chiral plasmonic nanostructures from static to dynamic. Taking advantages of the spherical metal nanomaterials own isotropy and the programable of DNA nanostructures, the chiral configuration of self-assembled plasmonic nanostructures mainly consider the overall geometry of chiral space, which is easy to expand to more chiral and complex structure. Researchers can arrange achiral metal nanoparticles including gold nanoparticles, silver nanoparticles and quantum dots to fabricate chiral plasmonic nanostructures by analyzing and simulating the optically active molecular analogs. In addition, the interest in self-assembly of chiral plasmonic nanostructures, such as gold nanorods, as anisotropic building blocks is growing quickly. Researchers have developed a variety of complex superstructures such as chiral tetrahedral nanoparticles, pyramid nanoparticles, helical structures and three-dimensional plasmonic nanostructures. DNA nanotechnology provides one of the few ways to form designed, complex structures with precise control over nanoscale features. As a result, plasmonic chiral nanostructures assembled by DNA allow for dynamic manipulation of chirality and reversible switching of strong CD responses, hold great promise for applications in adaptable nanophotonic circuitry, artificial nanomachinery, as well as optical sensing of molecular binding and interaction activities. This article briefly reviews the developments and achievements of chiral plasmonic nanostructures enabled by DNA nanotechnology. Firstly, we show chiral plasmonic nanostructures based on spherical AuNPs, including plasmonic helices, tetramers, and chiral geometric conformations. Then, to challenge the complex configurations and enhance the CD responses, anisotropic gold nanorods with larger extinction coefficients are utilized to fabricate chiral plasmonic nanostructures including dimers, tripod and superhelix. Finally, we introduce dynamic manipulation based on DNA nanostructures with the fast development of this interdisciplinary field. We envision that the combination of DNA nanotechnology and plasmonics will open an avenue toward a new generation of functional plasmonic systems with tailored optical properties and useful applications, including polarization conversion devices, biomolecular sensing, surface-enhanced Raman and fluorescence spectroscopy, and diffraction-limited optics.


Funded by

国家自然科学基金(21425103)

国家自然科学基金(21673280)

国家自然科学基金(21703282)

国家自然科学基金(21802163)


References

[1] Zhang S, Park Y S, Li J, et al. Negative refractive index in chiral metamaterials. Phys Rev Lett, 2009, 102: 023901 CrossRef ADS Google Scholar

[2] Agranat I, Caner H, Caldwell J. Putting chirality to work: The strategy of chiral switches. Nat Rev Drug Discov, 2002, 1: 753-768 CrossRef Google Scholar

[3] Ma W, Xu L, de Moura A F, et al. Chiral inorganic nanostructures. Chem Rev, 2017, 117: 8041-8093 CrossRef Google Scholar

[4] Ma W, Hao C, Sun M, et al. Tuning of chiral construction, structural diversity, scale transformation and chiroptical applications. Mater Horiz, 2018, 5: 141-161 CrossRef Google Scholar

[5] Zhao Y, Sun M, Ma W, et al. Biological molecules-governed plasmonic nanoparticle dimers with tailored optical behaviors. J Phys Chem Lett, 2017, 8: 5633-5642 CrossRef Google Scholar

[6] Ozbay E. Plasmonics: Merging photonics and electronics at nanoscale dimensions. Science, 2006, 311: 189-193 CrossRef ADS Google Scholar

[7] Schuller J A, Barnard E S, Cai W, et al. Plasmonics for extreme light concentration and manipulation. Nat Mater, 2010, 9: 193-204 CrossRef ADS Google Scholar

[8] Wang Z, Cheng F, Winsor T, et al. Optical chiral metamaterials: A review of the fundamentals, fabrication methods and applications. Nanotechnology, 2016, 27: 412001 CrossRef ADS Google Scholar

[9] Valev V K, Baumberg J J, Sibilia C, et al. Chirality and chiroptical effects in plasmonic nanostructures: Fundamentals, recent progress, and outlook. Adv Mater, 2013, 25: 2517-2534 CrossRef Google Scholar

[10] Luo Y, Chi C, Jiang M, et al. Plasmonic chiral nanostructures: Chiroptical effects and applications. Adv Opt Mater, 2017, 5: 1700040 CrossRef Google Scholar

[11] Seeman N C. Nucleic acid junctions and lattices. J Theor Biol, 1982, 99: 237-247 CrossRef Google Scholar

[12] Zhang F, Jiang S, Wu S, et al. Complex wireframe DNA origami nanostructures with multi-arm junction vertices. Nat Nanotech, 2015, 10: 779-784 CrossRef ADS Google Scholar

[13] Yan H, Park S H, Finkelstein G, et al. DNA-templated self-assembly of protein arrays and highly conductive nanowires. Science, 2003, 301: 1882-1884 CrossRef ADS Google Scholar

[14] He Y, Tian Y, Chen Y, et al. Sequence symmetry as a tool for designing DNA nanostructures. Angew Chem Int Ed, 2005, 44: 6694-6696 CrossRef Google Scholar

[15] He Y, Chen Y, Liu H, et al. Self-assembly of hexagonal DNA two-dimensional (2D) arrays. J Am Chem Soc, 2005, 127: 12202-12203 CrossRef Google Scholar

[16] Yin P, Hariadi R F, Sahu S, et al. Programming DNA tube circumferences. Science, 2008, 321: 824-826 CrossRef ADS Google Scholar

[17] Wei B, Dai M, Yin P. Complex shapes self-assembled from single-stranded DNA tiles. Nature, 2012, 485: 623-626 CrossRef ADS Google Scholar

[18] Ke Y, Ong L L, Shih W M, et al. Three-dimensional structures self-assembled from DNA bricks. Science, 2012, 338: 1177-1183 CrossRef ADS Google Scholar

[19] Ong L L, Hanikel N, Yaghi O K, et al. Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components. Nature, 2017, 552: 72-77 CrossRef ADS Google Scholar

[20] Rothemund P W K. Folding DNA to create nanoscale shapes and patterns. Nature, 2006, 440: 297-302 CrossRef ADS Google Scholar

[21] He Y, Ye T, Su M, et al. Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra. Nature, 2008, 452: 198-201 CrossRef ADS Google Scholar

[22] Douglas S M, Chou J J, Shih W M. DNA-nanotube-induced alignment of membrane proteins for NMR structure determination. Proc Natl Acad Sci USA, 2007, 104: 6644-6648 CrossRef ADS Google Scholar

[23] Douglas S M, Dietz H, Liedl T, et al. Erratum: Self-assembly of DNA into nanoscale three-dimensional shapes. Nature, 2009, 459: 1154 CrossRef ADS Google Scholar

[24] Dietz H, Douglas S M, Shih W M. Folding DNA into twisted and curved nanoscale shapes. Science, 2009, 325: 725-730 CrossRef ADS Google Scholar

[25] Han D, Pal S, Nangreave J, et al. DNA origami with complex curvatures in three-dimensional space. Science, 2011, 332: 342-346 CrossRef ADS Google Scholar

[26] Song J, Li Z, Wang P, et al. Reconfiguration of DNA molecular arrays driven by information relay. Science, 2017, 357: eaan3377 CrossRef Google Scholar

[27] Tikhomirov G, Petersen P, Qian L. Programmable disorder in random DNA tilings. Nat Nanotech, 2017, 12: 251-259 CrossRef ADS Google Scholar

[28] Tikhomirov G, Petersen P, Qian L. Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns. Nature, 2017, 552: 67-71 CrossRef ADS Google Scholar

[29] Fang W N, Fan C H, Liu H J. Effect of pH on the stability of DNA origami. Acta Polym Sin, 2017, (12): 1993–2000. Google Scholar

[30] Zhao Y, Xu L, Ma W, et al. Shell-engineered chiroplasmonic assemblies of nanoparticles for zeptomolar DNA detection. Nano Lett, 2014, 14: 3908-3913 CrossRef ADS Google Scholar

[31] Yan W, Xu L, Xu C, et al. Self-Assembly of Chiral Nanoparticle Pyramids with Strong R / S Optical Activity. J Am Chem Soc, 2012, 134: 15114-15121 CrossRef Google Scholar

[32] Shen X, Song C, Wang J, et al. Rolling up gold nanoparticle-dressed DNA origami into three-dimensional plasmonic chiral nanostructures. J Am Chem Soc, 2012, 134: 146-149 CrossRef Google Scholar

[33] Kuzyk A, Schreiber R, Fan Z, et al. DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response. Nature, 2012, 483: 311-314 CrossRef ADS arXiv Google Scholar

[34] Urban M J, Dutta P K, Wang P, et al. Plasmonic toroidal metamolecules assembled by DNA origami. J Am Chem Soc, 2018, 138: 5495-5498 CrossRef Google Scholar

[35] Mastroianni A J, Claridge S A, Alivisatos A P. Pyramidal and chiral groupings of gold nanocrystals assembled using DNA scaffolds. J Am Chem Soc, 2009, 131: 8455-8459 CrossRef Google Scholar

[36] Shen X, Asenjo-Garcia A, Liu Q, et al. Three-dimensional plasmonic chiral tetramers assembled by DNA origami. Nano Lett, 2013, 13: 2128-2133 CrossRef ADS Google Scholar

[37] Fan Z, Govorov A O. Plasmonic Circular Dichroism of Chiral Metal Nanoparticle Assemblies. Nano Lett, 2010, 10: 2580-2587 CrossRef ADS Google Scholar

[38] Fan Z, Zhang H, Govorov A O. Optical properties of chiral plasmonic tetramers: Circular dichroism and multipole effects. J Phys Chem C, 2013, 117: 14770-14777 CrossRef Google Scholar

[39] Ferry V E, Smith J M, Alivisatos A P. Symmetry breaking in tetrahedral chiral plasmonic nanoparticle assemblies. ACS Photonics, 2014, 1: 1189-1196 CrossRef Google Scholar

[40] Pal S, Deng Z, Wang H, et al. DNA directed self-assembly of anisotropic plasmonic nanostructures. J Am Chem Soc, 2011, 133: 17606-17609 CrossRef Google Scholar

[41] Zhan P, Dutta P K, Wang P, et al. Reconfigurable three-dimensional gold nanorod plasmonic nanostructures organized on DNA origami tripod. ACS Nano, 2017, 11: 1172-1179 CrossRef Google Scholar

[42] Lan X, Lu X, Shen C, et al. Au nanorod helical superstructures with designed chirality. J Am Chem Soc, 2014, 137: 457-462 CrossRef Google Scholar

[43] Shen C, Lan X, Zhu C, et al. Spiral patterning of Au nanoparticles on Au nanorod surface to form chiral AuNR@AuNP helical superstructures templated by DNA origami. Adv Mater, 2017, 29: 1606533 CrossRef Google Scholar

[44] Shen C, Lan X, Lu X, et al. Site-specific surface functionalization of gold nanorods using DNA origami clamps. J Am Chem Soc, 2016, 138: 1764-1767 CrossRef Google Scholar

[45] Lan X, Chen Z, Dai G, et al. Bifacial DNA origami-directed discrete, three-dimensional, anisotropic plasmonic nanoarchitectures with tailored optical chirality. J Am Chem Soc, 2013, 135: 11441-11444 CrossRef Google Scholar

[46] Liu Y, Lan X, Su Z, et al. Programmable supra-assembly of DNA surface adapter for tunable chiral directional self-assembly of gold nanorods. Angew Chem Int Ed, 2017, 56: 14824–14828. Google Scholar

[47] Hong F, Zhang F, Liu Y, et al. DNA origami: Scaffolds for creating higher order structures. Chem Rev, 2017, 117: 12584-12640 CrossRef Google Scholar

[48] Hu Q, Li H, Wang L, et al. DNA nanotechnology-enabled drug delivery systems. Chem Rev, 2018, : acs.chemrev.7b00663 CrossRef Google Scholar

[49] Lan X, Wang Q. Self-assembly of chiral plasmonic nanostructures. Adv Mater, 2016, 28: 10499-10507 CrossRef Google Scholar

[50] Liu N, Liedl T. DNA-assembled advanced plasmonic architectures. Chem Rev, 2018, 118: 3032-3053 CrossRef Google Scholar

[51] Zhang Y, Chao J, Liu H, et al. Transfer of two-dimensional oligonucleotide patterns onto stereocontrolled plasmonic nanostructures through DNA-origami-based nanoimprinting lithography. Angew Chem Int Ed, 2016, 55: 8036-8040 CrossRef Google Scholar

[52] Jiang Q, Liu Q, Shi Y, et al. Stimulus-responsive plasmonic chiral signals of gold nanorods organized on DNA origami. Nano Lett, 2017, 17: 7125-7130 CrossRef ADS Google Scholar

[53] Kuzyk A, Schreiber R, Zhang H, et al. Reconfigurable 3D plasmonic metamolecules. Nat Mater, 2014, 13: 862-866 CrossRef ADS Google Scholar

[54] Zhou C, Duan X, Liu N. A plasmonic nanorod that walks on DNA origami. Nat Commun, 2015, 6: 8102 CrossRef ADS Google Scholar

[55] Yan Y, Chen J I L, Ginger D S. Photoswitchable oligonucleotide-modified gold nanoparticles: Controlling hybridization stringency with photon dose. Nano Lett, 2012, 12: 2530-2536 CrossRef ADS Google Scholar

  • Figure 1

    (Color online) Spherical metal nanomaterials are assembled into chiral plasma nanostructures. (a) DNA-bridged pairs of gold and silver shells around the nanoparticle heterodimers enables spectral modulation of their chiral plasmonic bands in 400–600 nm region[30]. (b) A family of self-assembled chiral pyramids made from multiple metal and/or semiconductor nanoparticles[31]. (c) Fifteen AuNPs are assembled on a rectangular origami sheet. Addition of the folding strands leads to rolling and subsequent stapling of the 2D sheet into a hollow tube. As a consequence, the AuNPs are arranged into a 3D helix[32]. (d) Plasmonic helices created by arranging AuNPs on origami bundles and the measured CD spectra[33]. (e) AuNPs are assembled in a helical fashion along an origami ring to form a chiral plasmonic toroidal structure[34]

  • Figure 2

    (Color online) Gold nanorods (AuNRs) are assembled into chiral plasmonic nanostructures. (a) AuNR dimer structures with various predetermined inter-rod angles and relative distances via triangular DNA origami[40]. (b) A 3D reconfigurable plasmonic nanostructure with controllable, reversible DNA origami tripod[41]. (c) By designing the "X" pattern of the arrangement of DNA capturing strands on both sides of a two-dimensional DNA origami template, AuNRs were assembled into AuNR superstructures with the origami intercalated between neighboring AuNRs[42]

  • Figure 3

    (Color online) DNA-assembled plasmonic nanostructures for dynamic manipulation. (a) A stimulus-responsive plasmonic nanosystem based on DNA origami-organized gold nanorods[52]. (b) Reconfigurable 3D plasmonic nanostructures consist of AuNRs hosted on switchable DNA origami templates based on toehold mediated chain replacement[53]. (c) Plasmonic walker that can perform stepwise walking on origami[54]

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