SCIENCE CHINA Information Sciences, Volume 64 , Issue 1 : 112203(2021) https://doi.org/10.1007/s11432-020-2995-5

Wearable wireless real-time cerebral oximeter for measuring regional cerebral oxygen saturation

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  • ReceivedApr 23, 2020
  • AcceptedJun 29, 2020
  • PublishedDec 14, 2020



This work was partially supported by National Key Research and Development Program of China (Grant No. 2017YFB1002502), National Natural Science Foundation of China (Grant Nos. 31571003, U1636121), Key Programs of Science and Technology Commission Foundation of Beijing (Grant No. Z181100003818004), S and Supportive Project for Teachers at Beijing Information Science and Technology University (2018-2020) (Grant No. 5029011103), Beijing Municipal Education Commission Science and Technology Program (Grant Nos. KM202011232008, KM201911232019). We appreciate the English editing assistance of Drs. Rhoda E. and Edmund F. Perozzi.


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  • Figure 1

    (Color online) Schematic diagram of the wireless cerebral oximeter (WORTH band). LED${:}$ light-emitting diode; ADC${:}$ analog to digital converter; EEPROM${:}$ electrically erasable programmable read only memory; RTC${:}$ real-time clock; I2C${:}$ inter-integrated circuit.

  • Figure 2

    (Color online) The wearable wireless cerebral oximeter (WORTH band). (a) The arrangement of optical parts of the WORTH band; (b) the exploded view of the WORTH band; (c) the GUI interface on a smart phone.

  • Figure 3

    The experimental protocol of the controlled hypoxia experiment.

  • Figure 4

    (Color online) Tissue oxygen saturation of a single participant during the controlled hypoxia experiment. The red, blue, and green curves indicate the rSO2 of the WORTH band, the rSO2 of the FORE-SIGHT oximeter, and the SpO2, respectively. The duration of the low concentration oxygen inhalation is indicated by the space between the two gray lines.

  • Figure 5

    Correlation results of different oxygen saturations for the controlled hypoxia experiment. (a) Correlation of the rSO2 between the WORTH band and the FORE-SIGHT oximeter; (b) correlation between the rSO2 of the WORTH band and the pulse oxygen saturation SpO2; (c) correlation between the rSO2 of the FORE-SIGHT oximeter and SpO2.

  • Figure 6

    Experimental protocol of the squat-to-stand experiment.

  • Figure 7

    (Color online) The group-averaged results of the squat-to-stand experiment.